Timor BAASOV: search on Z-Library

The world's largest scientific articles store. 70,000,000+ articles for free.

Don't use scam websites

1

Design, Synthesis, and Evaluation of Novel Fluoroquinolone−Aminoglycoside Hybrid Antibiotics

Pokrovskaya, Varvara, Belakhov, Valery, Hainrichson, Mariana, Yaron, Sima, Baasov, Timor

Journal:

Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 376 KB

english, 2009

2

Dual-acting hybrid antibiotics: a promising strategy to combat bacterial resistance

Pokrovskaya, Varvara, Baasov, Timor

Journal:

Expert Opinion on Drug Discovery

Year:

2010

Language:

english

File:

PDF, 842 KB

english, 2010

3

Towards a new class of synthetic antibacterials acting on lipopolysaccharide biosynthesis

Timor Baasov, Valery Belakhov

Journal:

Drug Development Research

Year:

2000

Language:

english

File:

PDF, 232 KB

english, 2000

4

Combined Chemical-Enzymatic Assembly of Aminoglycoside Derivatives with N-1-AHB Side Chain

Igor Nudelman, Lilach Chen, Nicholas M. Llewellyn, El-Habib Sahraoui, Marina Cherniavsky, Jonathan B. Spencer, Timor Baasov

Journal:

Advanced Synthesis & Catalysis

Year:

2008

Language:

english

File:

PDF, 365 KB

english, 2008

5

C=C-Streckschwingungsfrequenzen in Modellverbindungen der Protonierten Schiff-Base des Retinals

Timor Baasov, Dr. Mordechai Sheves

Journal:

Angewandte Chemie

Year:

1984

Language:

german

File:

PDF, 215 KB

german, 1984

6

Dual Effect of Synthetic Aminoglycosides: Antibacterial Activity against Bacillus anthracis and Inhibition of Anthrax Lethal Factor

Micha Fridman, Valery Belakhov, Lac V. Lee, Fu-Sen Liang, Chi-Huey Wong, Timor Baasov

Journal:

Angewandte Chemie

Year:

2005

Language:

english

File:

PDF, 142 KB

english, 2005

7

CC Stretching Frequencies in Model Compounds of the Protonated Retinal Schiff Base

Timor Baasov, Dr. Mordechai Sheves

Journal:

Angewandte Chemie International Edition

Year:

1984

Language:

english

File:

PDF, 223 KB

english, 1984

8

Dual Effect of Synthetic Aminoglycosides: Antibacterial Activity against Bacillus anthracis and Inhibition of Anthrax Lethal Factor

Micha Fridman, Valery Belakhov, Lac V. Lee, Fu-Sen Liang, Chi-Huey Wong, Timor Baasov

Journal:

Angewandte Chemie International Edition

Year:

2005

Language:

english

File:

PDF, 143 KB

english, 2005

9

Differential Selectivity of Natural and Synthetic Aminoglycosides towards the Eukaryotic and Prokaryotic Decoding A Sites

Jiro Kondo, Mariana Hainrichson, Igor Nudelman, Dalia Shallom-Shezifi, Christopher M. Barbieri, Daniel S. Pilch, Eric Westhof, Timor Baasov

Journal:

Year:

2007

Language:

english

File:

PDF, 1.04 MB

english, 2007

10

Cover Picture: Differential Selectivity of Natural and Synthetic Aminoglycosides towards the Eukaryotic and Prokaryotic Decoding A Sites (ChemBioChem 14/2007)

Jiro Kondo, Mariana Hainrichson, Igor Nudelman, Dalia Shallom-Shezifi, Christopher M. Barbieri, Daniel S. Pilch, Eric Westhof, Timor Baasov

Journal:

Year:

2007

File:

PDF, 35 KB

2007

11

ChemInform Abstract: Programmable One-Pot Oligosaccharide Synthesis.

Zhiyuan Zhang, Ian R. Ollmann, Xin-Shan Ye, Ralf Wischnat, Timor Baasov, Chi-Huey Wong

Journal:

Year:

1999

File:

PDF, 23 KB

1999

12

ChemInform Abstract: Studies Towards the Synthesis and Evaluation of Mechanism-Based Inhibitors of Kdo8P Synthase — A Key Enzyme in the Biosynthesis of Lipopolysaccharides

Timor Baasov, Valery Belakhov

Journal:

Year:

2000

File:

PDF, 25 KB

2000

13

ChemInform Abstract: One-Pot Synthesis of Glucosamine Oligosaccharides.

Micha Fridman, Dmitry Solomon, Shay Yogev, Timor Baasov

Journal:

Year:

2002

File:

PDF, 23 KB

2002

14

A New Class of Branched Aminoglycosides: Pseudo-Pentasaccharide Derivatives of Neomycin B.

Micha Fridman, Valery Belakhov, Sima Yaron, Timor Baasov

Journal:

Year:

2004

File:

PDF, 50 KB

2004

15

Interactions between protonated retinal schiff base and various counter ions: A study by two-dimensional NOE NMR spectroscopy

Rodolfo Ghirlando, Elisha Berman, Timor Baasov, Mordechai Sheves

Journal:

Magnetic Resonance in Chemistry

Year:

1987

Language:

english

File:

PDF, 397 KB

english, 1987

16

A new model for the stereoselective construction of the Kdo structure through a mechanism similar to that suggested for the enzyme Kdo8P synthase

Shoucheng Du, Dorit Plat, Timor Baasov

Journal:

Tetrahedron Letters

Year:

1996

Language:

english

File:

PDF, 242 KB

english, 1996

17

Branched aminoglycosides: Biochemical studies and antibacterial activity of neomycin B derivatives

Mariana Hainrichson, Varvara Pokrovskaya, Dalia Shallom-Shezifi, Micha Fridman, Valery Belakhov, Dina Shachar, Sima Yaron, Timor Baasov

Journal:

Bioorganic & Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 318 KB

english, 2005

18

Structure–toxicity relationship of aminoglycosides: Correlation of 2′-amine basicity with acute toxicity in pseudo-disaccharide scaffolds

Lilach Chen, Mariana Hainrichson, Dmitry Bourdetsky, Amram Mor, Sima Yaron, Timor Baasov

Journal:

Bioorganic & Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 721 KB

english, 2008

19

Redesign of aminoglycosides for treatment of human genetic diseases caused by premature stop mutations

Igor Nudelman, Annie Rebibo-Sabbah, Dalia Shallom-Shezifi, Mariana Hainrichson, Ido Stahl, Tamar Ben-Yosef, Timor Baasov

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 228 KB

english, 2006

20

Synthesis and evaluation of a mechanism-based inhibitor of KDO8P synthase

Valery Belakhov, Ekaterina Dovgolevsky, Emilia Rabkin, Smadar Shulami, Yuval Shoham, Timor Baasov

Journal:

Carbohydrate Research

Year:

2004

Language:

english

File:

PDF, 439 KB

english, 2004

21

An efficient chemical-enzymatic synthesis of 4-nitrophenyl β-xylobioside: a chromogenic substrate for xylanases

Adva Mechaly, Valery Belakhov, Yuval Shoham, Timor Baasov

Journal:

Carbohydrate Research

Year:

1997

Language:

english

File:

PDF, 395 KB

english, 1997

22

Synthesis of novel phosphonate analogue of Kdo as a tool for the design of potent inhibitors for lipopolysaccharide biosynthesis

Shani Sheffer-Dee-Noor, Valery Belakhov, Timor Baasov

Journal:

Tetrahedron Letters

Year:

1994

Language:

english

File:

PDF, 388 KB

english, 1994

23

Towards the synthesis of the putative reaction intermediate in the Kdo8P synthase-catalyzed reaction. Synthesis and evaluation of 3-deoxy-d-manno-2-octulosonate-2-phosphate

Amnon Kohen, Valery Belakhov, Timor Baasov

Journal:

Tetrahedron Letters

Year:

1994

Language:

english

File:

PDF, 351 KB

english, 1994

24

A blue shift of protonated retinal schiff base. A model study for bacteriorhodopsin

Mordechai Sheves, Timor Baasov

Journal:

Tetrahedron Letters

Year:

1983

Language:

english

File:

PDF, 191 KB

english, 1983

25

Photochemistry of thioanhydrides. Photofragmentation of cis-1,2-dihydrophthalic thioanhydrides

Timor Baasov, Benzion Fuchs

Journal:

Tetrahedron Letters

Year:

1982

Language:

english

File:

PDF, 171 KB

english, 1982

26

Binding of the natural substrates and products to KDO8P synthase: 31P and 13C solution NMR characterization

Lilia Kaustov, Timor Baasov, Asher Schmidt

Journal:

Bioorganic Chemistry

Year:

2003

Language:

english

File:

PDF, 204 KB

english, 2003

27

Stereochemistry of the KDO8P synthase. An efficient synthesis of the 3-fluoro analogues of KDO8P

Amnon Kohen, Ronit Berkovich, Valery Belakhov, Timor Baasov

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1993

Language:

english

File:

PDF, 489 KB

english, 1993

28

Insight into the catalytic mechanism of KDO8P synthase. Synthesis and evaluation of the isosteric phosphonate mimic of the putative cyclic intermediate

Shani Sheffer-Dee-Noor, Valery Belakhov, Timor Baasov

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1993

Language:

english

File:

PDF, 476 KB

english, 1993

29

A combined chemical-enzymatic synthesis of a new phosphoramidate analogue of phosphoenolpyruvate

Shani Sheffer-Dee-Noor, Timor Baasov

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1993

Language:

english

File:

PDF, 345 KB

english, 1993

30

1-(Dihydroxyphosphynyl)vinyl phosphate: The phosphonate analogue of phosphoenolpyruvate is a pH-dependent substrate of Kdo8P synthase

Yaakov Benenson, Valery Belakhov, Timor Baasov

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1996

Language:

english

File:

PDF, 346 KB

english, 1996

31

Synthesis and evaluation of putative oxocarbenium intermediate mimic in the KDO8P synthase-catalyzed reaction as a tool for the design of potent inhibitors for lipopolysaccharide biosynthesis

Shoucheng Du, Hana Tsipori, Timor Baasov

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 257 KB

english, 1997

32

Catalytic mechanism of KDO8P synthase. Pre-steady-state kinetic analysis using rapid chemical quench flow methods

Po-Huang Liang, Amnon Kohen, Timor Baasov, Karen S. Anderson

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 375 KB

english, 1997

33

Catalytic mechanism of KDO8P synthase: synthesis and evaluation of a putative reaction intermediate

Francis Wallace D'Souza, Yaakov Benenson, Timor Baasov

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 383 KB

english, 1997

34

Towards the development of novel antibiotics: synthesis and evaluation of a mechanism-based inhibitor of Kdo8P synthase

Shoucheng Du, Hana Faiger, Valery Belakhov, Timor Baasov

Journal:

Bioorganic & Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 323 KB

english, 1999

35

Biochemical characterization and identification of catalytic residues in α-glucuronidase from Bacillus stearothermophilus T-6

Galia Zaide, Dalia Shallom, Smadar Shulami, Gennady Zolotnitsky, Gali Golan, Timor Baasov, Gil Shoham, Yuval Shoham

Journal:

Year:

2001

Language:

english

File:

PDF, 1.78 MB

english, 2001

36

Readthrough of nonsense mutations in Rett syndrome: evaluation of novel aminoglycosides and generation of a new mouse model

Cornelia Brendel, Valery Belakhov, Hauke Werner, Eike Wegener, Jutta Gärtner, Igor Nudelman, Timor Baasov, Peter Huppke

Journal:

Journal of Molecular Medicine

Year:

2011

Language:

english

File:

PDF, 763 KB

english, 2011

37

Suppression ofCFTRpremature termination codons and rescue of CFTR protein and function by the synthetic aminoglycoside NB54

Steven M. Rowe, Peter Sloane, Li Ping Tang, Kyle Backer, Marina Mazur, Jessica Buckley-Lanier, Igor Nudelman, Valery Belakhov, Zsuzsa Bebok, Erik Schwiebert, Timor Baasov, David M. Bedwell

Journal:

Journal of Molecular Medicine

Year:

2011

Language:

english

File:

PDF, 588 KB

english, 2011

38

In vitro and ex vivo suppression by aminoglycosides ofPCDH15nonsense mutations underlying type 1 Usher syndrome

Annie Rebibo-Sabbah, Igor Nudelman, Zubair M. Ahmed, Timor Baasov, Tamar Ben-Yosef

Journal:

Year:

2007

Language:

english

File:

PDF, 421 KB

english, 2007

39

Cloning, expression, and biochemical characterization of 3-deoxy-d-manno-2-octulosonate-8-phosphate (KDO8P) synthase from the hyperthermophilic bacteriumAquifex pyrophilus

Smadar Shulami, Orit Yaniv, Emilia Rabkin, Yuval Shoham, Timor Baasov

Journal:

Year:

2003

Language:

english

File:

PDF, 1.08 MB

english, 2003

40

Repairing faulty genes by aminoglycosides: Development of new derivatives of geneticin (G418) with enhanced suppression of diseases-causing nonsense mutations

Igor Nudelman, Dana Glikin, Boris Smolkin, Mariana Hainrichson, Valery Belakhov, Timor Baasov

Journal:

Bioorganic & Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 812 KB

english, 2010

41

Mechanistic studies of 3-deoxy-d-manno-2-octulosonate-8-phosphate synthase from Escherichia coli

Amnon KOHEN, Abla JAKOB, Timor BAASOV

Journal:

Year:

1992

Language:

english

File:

PDF, 778 KB

english, 1992

42

Catalytic mechanism of 3-deoxy-d-manno-2-octulosonate-8-phosphate synthase : The use of synthetic analogues to probe the structure of the putative reaction intermediate

Timor BAASOV, Shani SHEFFER-DEE-NOOR, Amnon KOHEN, Abla JAKOB, Valery BELAKHOV

Journal:

Year:

1993

Language:

english

File:

PDF, 1.10 MB

english, 1993

43

Crystal Structures of Escherichia coli KDO8P Synthase Complexes Reveal the Source of Catalytic Irreversibility

Radion Vainer, Valery Belakhov, Emilia Rabkin, Timor Baasov, Noam Adir

Journal:

Journal of Molecular Biology

Year:

2005

Language:

english

File:

PDF, 689 KB

english, 2005

44

The designer aminoglycoside NB84 significantly reduces glycosaminoglycan accumulation associated with MPS I-H in the Idua-W392X mouse

Dan Wang, Valery Belakhov, Jeyakumar Kandasamy, Timor Baasov, Su-Chen Li, Yu-Teh Li, David M. Bedwell, Kim M. Keeling

Journal:

Molecular Genetics and Metabolism

Year:

2012

Language:

english

File:

PDF, 974 KB

english, 2012

45

Suppression of a Nonsense Mutation in a Mouse Model Of Hurler Syndrome

Kim Keeling, Dan Wang, Valery Belakhov, Jeyakumar Kandasamy, Timor Baasov, Su-Chen Li, Yu-Teh Li, Yanying Dai, Sandanandan Velu, David Bedwell, Kim Keeling

Journal:

Molecular Genetics and Metabolism

Year:

2012

Language:

english

File:

PDF, 57 KB

english, 2012

46

Glutamic acid 160 is the acid-base catalyst of β-xylosidase from Bacillus stearothermophilus T-6: a family 39 glycoside hydrolase

Tsafrir Bravman, Adva Mechaly, Smadar Shulami, Valery Belakhov, Timor Baasov, Gil Shoham, Yuval Shoham

Journal:

Year:

2001

Language:

english

File:

PDF, 158 KB

english, 2001

47

Stereochemistry of family 52 glycosyl hydrolases: a β-xylosidase from Bacillus stearothermophilus T-6 is a retaining enzyme

Tsafrir Bravman, Gennady Zolotnitsky, Smadar Shulami, Valery Belakhov, Dmitry Solomon, Timor Baasov, Gil Shoham, Yuval Shoham

Journal:

Year:

2001

Language:

english

File:

PDF, 366 KB

english, 2001

48

The identification of the acid–base catalyst of α-arabinofuranosidase from Geobacillus stearothermophilus T-6, a family 51 glycoside hydrolase

Dalia Shallom, Valery Belakhov, Dmitry Solomon, Sara Gilead-Gropper, Timor Baasov, Gil Shoham, Yuval Shoham

Journal:

Year:

2002

Language:

english

File:

PDF, 152 KB

english, 2002

49

A comparative evaluation of NB30, NB54 and PTC124 in translational read-through efficacy for treatment of an USH1C nonsense mutation

Goldmann, Tobias, Overlack, Nora, Möller, Fabian, Belakhov, Valery, van Wyk, Michiel, Baasov, Timor, Wolfrum, Uwe, Nagel-Wolfrum, Kerstin

Journal:

EMBO Molecular Medicine

Year:

2012

Language:

english

File:

PDF, 1.18 MB

english, 2012

50

Biotransformations of propenylbenzenes by an Arthrobacter sp. and its t-anethole blocked mutants

Eyal Shimoni, Timor Baasov, Uzi Ravid, Yuval Shoham

Journal:

Journal of Biotechnology

Year:

2003

Language:

english

File:

PDF, 256 KB

english, 2003